E-64c
CAY-10007964-5 5 mg
Synonyms: Loxistatin Acid|NSC 694279
Data Sheet: 
SDS:
SDS:
CAS
76684-89-4
Formulation
A crystalline solid
Purity
≥98%
MW
314,4
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
E-64c is an active metabolite of the protease inhibitor E-64d (Item No. 13533).{14249,58182,54647,54648} E-64c inhibits the cysteine proteases cathepsin B, cathepsin H, and papain but not the serine proteases trypsin, chymotrypsin, or elastase.{17474,54649} It reduces the autocatalytic activity of the foot-and-mouth-disease virus (FMDV) leader protease when used at concentrations ranging from 0.1 to 1 mg/ml.{54647} E-64c reduces infection of HEK293T cells by an HIV-based virus system pseudotyped with severe acute respiratory syndrome coronavirus (SARS-CoV) surface glycoprotein, also known as the spike glycoprotein, in a concentration-dependent manner.{54648}
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
