Danicopan
CAY-32737-10 10 mg
Data Sheet: 
SDS:
SDS:
CAS
1903768-17-1
Formulation
A solid
Purity
≥98%
MW
580,4
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
Danicopan is an inhibitor of Factor D, a protease in the alternative complement pathway (APC; IC50 = 15 nM in a cell-free assay).{60851} It is selective for Factor D over a panel of 12 serine proteases when used at a concentration of 10 µM. Danicopan inhibits hemolysis of erythrocytes isolated from patients with paroxysmal nocturnal hemoglobinuria (IC50s = 4-27 nM). Danicopan (200 mg/kg, p.o.) suppresses APC activity in monkeys.{60851}
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
