CASIN
CAY-17694-1 1 mg
Data Sheet: 
SDS:
SDS:
CAS
425399-05-9
Formulation
A crystalline solid
Purity
≥95%
MW
306,4
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
The Rho family of GTPases regulates diverse signal transduction pathways. One member, the cell division control protein 42 homolog (Cdc42), is involved in filopodia function, cell polarity, cell cycling, and other processes.{24682} CASIN is an indole-based small molecule that inhibits activation of the Cdc42 GTPase (IC50 = 2 µM for inhibiting actin assembly in PIP2-stimulated actin polymerization assays).{28862} This compound has been used to explore the role of Cdc42 in the division, survival, and differentiation of hematopoietic stem cells.{28863,28864}
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
