Bepridil (hydrochloride)
CAY-19645-25 25 mg
Data Sheet: 
SDS:
SDS:
CAS
68099-86-5
Formulation
A crystalline solid
Purity
≥98%
MW
403
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
Bepridil is a dihydropyridine that has anti-anginal and anti-arrhythmic actions by blocking calcium channels in heart and smooth muscle.{22485,28732} It is recognized as a non-selective channel blocker, altering myocardial Ca2+, Na+, and K+ currents.{31412} For example, it blocks voltage-gated Ca2+ (Cav3.2) and K+ (hERG and KCNQ4) channels, sarcoplasmic ATP-sensitive K+ (KATP) channels, and Na+-activated (KNa) channels (IC50s = 7.1, 22, 9.4, 10, and 2.2 µM, respectively).{24593,31415,31413,28732} It also activates mitochondrial ATP-sensitive KATP channels (ED50 = 27.5 µM).{31414}
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
