
Reactivity
Human, Mouse
Source / Host
HEK 293 cells
Specificity
Binds mouse and human BAFF and APRIL.
Purity
>95% (SDS-PAGE)
MW
~35kDa (SDS-PAGE)
Shipment
BI
Short Term Storage
+4°C
Long Term Storage
-20°C
Shelf Life
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Description
Protein. The extracellular domain of mouse BCMA (aa 1-46) is fused at the C-terminus to the Fc portion of human IgG1. Source: HEK 293 cells. Endotoxin content: <0.01EU/µg purified protein (LAL test; Lonza). Lyophilized. Contains PBS. Binds mouse and human BAFF and APRIL. Purity: >95% (SDS-PAGE). BCMA is a receptor for BAFF and APRIL. It promotes B cell survival and plays a role in the regulation of humoral immunity. It's downstream signaling is dependent on NF-kappaB and JNK.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).