
CAS
1011529-10-4
Formulation
A solid
Purity
≥95%
MW
286,2
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
Azvudine is a nucleoside reverse transcriptase inhibitor (NRTI).{68537} It reduces viral infectivity in HIV-1-infected HEK293T cells (EC50 = 0.063 nM) and reduces viral replication in 2209-23 cells stably transfected with hepatitis C virus (HCV) genotype 1b (EC50 = 24 nM).{68537,68538} In vivo, azvudine (0.7 mg/kg) reduces viral load and the number of lung ground-glass opacities observed via chest X-ray in a rhesus macaque model of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.{68539}
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).