CAS
1883711-97-4
Formulation
A solid
Purity
≥98%
MW
370,8
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
AM0902 is a transient receptor potential ankyrin 1 (TRPA1) antagonist (IC50 = 0.131 µM for the human receptor in a calcium mobilization assay).{62973} It is selective for human TRPA1 over human transient receptor potential vanilloid 1 (TRPV1) and TRPV4, rat TRPV1, TRPV3, and transient receptor potential melastatin 8 (TRPM8), and a panel of 40 additional targets at 10 µM. In vivo, AM0902 (10 and 30 mg/kg) reduces the number of tail flinches induced by the TRPA1 agonist allyl isothiocyanate (AITC) in rats.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).