CAS
899431-18-6
Formulation
A solid
Purity
≥98%
MW
342,6
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A-438079 is a competitive antagonist of the nucleotide receptor P2X7 (pIC50 = 6.9).{22914} It inhibits both calcium flux and IL-1β release mediated by P2X7 while not affecting the activity of other P2X receptors.{22914,22913} A-438079 is effective in evaluating the role of P2X7 in nociception, oxidative stress, and apoptosis in cells and animals.{22915,22916,22917}
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).