3,3',5'-Triiodo-L-thyronine
CAY-17598-25 25 mg
Data Sheet: 
SDS:
SDS:
CAS
5817-39-0
Formulation
A crystalline solid
Purity
≥95%
MW
651
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
3,3',5’-Triiodo-L-thyronine, also known as reverse T3 (rT3), is a thyroid hormone generated by deiodination of the prohormone thyroxine. It is about 1,000-fold less active at the thyroid hormone receptors TRα and TRβ than 3,3',5-triiodo-L-thyronine (Item No. 16028) and commonly described as inactive.{28789,28791} However, high serum levels of rT3 are found in neonates and in certain conditions.{28795,28793,28790,28792} It reportedly activates TRΔα1, a native form of TRα that lacks a nuclear localization signal and functions in the cytoplasm.{28794} Through this action, rT3 initiates actin polymerization, particularly in astrocytes and neurons.{28794}
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
